Histone Marks Direct Chromosome Segregation

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Histone Marks Direct Chromosome Segregation

Germline stem cells divide asymmetrically, producing a self-renewing stem cell and a differentiating progenitor. Xie et al. now show that this depends on two asymmetric events that together partition a genome copy, carrying the old histones to the stem cell daughter and a copy with new, unmarked histones to the differentiating daughter.

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ژورنال

عنوان ژورنال: Cell

سال: 2015

ISSN: 0092-8674

DOI: 10.1016/j.cell.2015.10.043